In clinical trials, non-diabetic individuals taking semaglutide experienced significant weight loss, with average weight loss ranging from 10% to 15% of initial body weight over 6-12 months of treatment
The decision framework is straightforward: Need to lose less than 10% of body weight
The Intensifying GLP-1 Race While Novo Nordisk recently secured FDA approval for an oral version of semaglutide becoming the first to market an oral GLP-1RA for obesity Eli Lilly continues to lead in injectable sales with: Zepbound (obesity) Mounjaro (type 2 diabetes) Lilly is also awaiting an FDA decision on its oral candidate, orforglipron
Zhao, W., Zhang, X., Zhou, Z., Sun, B., Gu, W., Liu, J., & Zhang, H
Severe Gastrointestinal Reactions The most common complications involve your digestive tract